Do mosquitoes get the mumps?, part III
Part III. Serendipity strikes when we Blink In which we find an unexpected result when we Blink while looking at the mumps polymerase. This is the third in a five part series on an unexpected discovery...
View ArticleDo mosquitoes get the mumps?, part IV
Part IV. Assembling the details and making the case for a novel paramyxovirus This is the fourth in a five part series on an unexpected discovery of a paramyxovirus in a mosquito. In this part, we take...
View ArticleA general method and good student project for finding interesting anomalies...
Do mosquitoes get the mumps? Part V. A general method for finding interesting things in GenBank This is the last in a five part series on an unexpected discovery of a paramyxovirus in mosquitoes and a...
View ArticleWhy would a mutation in Google-cofounder, Sergey Brin, cause Parkinson’s...
Lots of bloggers in the DNA network have been busy these past few days writing about Google’s co-founder Sergey Brin, his blog, his wife’s company (23andme), and his mutation in the LRRK2 gene. I was a...
View ArticleDigital Biology Friday: Let’s go on a treasure hunt!
Let’s play anomaly! Most of this week, I’ve written about the fun time I had playing around with NCBI’s Blink database and finding evidence that at least one mosquito, Aedes aegypti, seems to have been...
View ArticleWhy would we be able to detect more genetic variation by blasting with...
We’ll have a blast, I promise! But there’s one little thing we need to discuss first… I want to explain why I’m going to use nucleotide sequences for the blast search. (I used protein the other day)....
View ArticleWhy don’t we finish the human genome first?
One of the interesting things I learned today was that many people are calling for the genome sequences of the chimps and Macaques to be finished. This is especially amusing because the human genome...
View Article$1000 Genomes for $2000
Getting an accurate genome sequence requires that you collect the data at least twice argue Robasky, Lewis, and Church in their recent opinion piece in Nat. Rev. Genetics [1]. The DNA sequencing world...
View ArticleDevelopment and Role of the Human Reference Sequence in Personal Genomics
A few weeks back, we published a review about the development and role of the human reference genome. A key point of the reference genome is that it is not a single sequence. Instead it is an assembly...
View ArticleDNA: it’s in your blood
Did you know small fragments of DNA are circulating in your blood stream? These short pieces of DNA are left behind after cells self-destruct. This self-destruction, or apoptosis, is a normal process....
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